Human herpesvirus 8-unrelated primary effusion lymphoma-like lymphoma that developed during myelodysplastic syndrome

Primary effusion lymphoma (PEL) is a large B-cell that only proliferates proliferating in the body cavity. It associated with human herpesvirus 8 (HHV8).HHV8 negative lymphoma, which different from PEL many ways, has also been reported and referred to as HHV8-unrelated PEL-like lymphoma. This very rare its clinical characteristics have not fully clarified.A 79-year-old male developed HHV8-negative primary during treatment for myelodysplastic syndrome.Abdominal computed tomography revealed abdominal effusion, but did show any evidence of tumor mass or lymph node enlargement. A cytological analysis his pleural atypical lymphoid cells were CD10, positive CD19 CD20. Corticosteroids administered treat effusion; however, patient died an exacerbation on 20th day after initiation corticosteroid therapy. We herein report case HIV seronegative elderly